The developed approach provides two means of directly validating synthesized hardware designs. The first allows the original high-level model written in C or C++ to be directly coupled to the synthesized hardware, abstracting away the traditional gate-level view of designs. A high-level programmatic interface allows the synthesized design to be validated directly by the software reference model. The second approach provides an alternative view to FPGAs within the scope of a traditional software debugger. This debug framework leverages partially reconfigurable regions to accelerate the modification of dynamic, software-like breakpoints for low-level analysis and provides a automatable, scriptable, command-line interface directly to a running design on an FPGA.